Anti-Human MUC1 Recombinant Antibody (1B2) (CAT#: TAB-439MZ)
This antibody was produced by immunizing mice by using 2,3ST glycopeptide as an antigen. It can recognize a cancer-specific sugar chain significantly and specifically, and can also recognize and kill a cancer cell capable of expressing MUC1 that has such a cancer-cell-specific sugar chain. This antibody does not bind to a normal cell and is specific to a cancer cell. It reacts strongly with breast cancer cells while responding poorly to the mammary epithelial cells, which shows cytotoxic activity in breast cancer cells.
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SDS-PAGE
Figure 1 Anti-Human MUC1 Recombinant Antibody (TAB-439MZ) in SDS-PAGE
SDS-PAGE analysis of TAB-439MZ in reduced (Lane 1) and non-reduced (Lane 2) conditions.
SEC-HPLC
Figure 2 Anti-Human MUC1 Recombinant Antibody (TAB-439MZ) in HPLC
SEC-HPLC analysis of TAB-439MZ shows the purity is greater than 95%.
WB
Figure 3 Anti-Human MUC1 Recombinant Antibody (TAB-439MZ) in WB
Western blot analysis of TAB-439MZ was performed with MUC1 Protein (His Tag).
TAB-439MZ incubation concentration: 2 ng/μL.
The secondary antibody: HRP-Anti-Mouse IgG (H+L)
Lane 1: Reduced Antigen (0.1 μg)
Lane 2: Reduced Antigen (0.3 μg)
Lane 3: Reduced Antigen (0.6 μg)
WB
Figure 4 Anti-MUC1 Recombinant Antibody (TAB-439MZ) in WB
WB analysis of TAB-439MZ was performed by coating with Human MUC1 protein, His tag.
Specifications
- Host Species
- Mouse
- Specificity
- Human
- Clone
- 1B2
- Applications
- Flow Cytometry
- Related Disease
- Breast cancer
Target
- Alternative Names
- MUC1; mucin 1, cell surface associated; EMA; MCD; PEM; PUM; KL-6; MAM6; MCKD; PEMT; CD227; H23AG; MCKD1; MUC-1; ADMCKD; ADMCKD1; CA 15-3; MUC-1/X; MUC1/ZD; MUC-1/SEC; mucin-1; episialin; DF3 antigen; H23 antigen; cancer antigen 15-3; krebs von den Lungen-6; mucin 1, transmembrane; carcinoma-associated mucin; polymorphic epithelial mucin; peanut-reactive urinary mucin; tumor associated epithelial mucin; breast carcinoma-associated antigen DF3; tumor-associated epithelial membrane antigen; Medullary cystic kidney disease, autosomal dominant;
- Gene ID
- 4582
- UniProt ID
- P15941
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-2049-VHH | Recombinant Anti-human MUC1 VHH Single Domain Antibody | WB, IP, ChiP, Neut, ELISA | Llama VHH |
| HPAB-AP504-YC | Recombinant Camel Anti-MUC1 Single Domain Antibody (HPAB-AP504-YC) | FC | Camel VHH |
| HPAB-AP505-YC | Recombinant Camel Anti-MUC1 Single Domain Antibody (HPAB-AP505-YC) | ELISA | Camel VHH |
| HPAB-0736-YJ-VHH | Camelid Anti-MUC1 Recombinant Single Domain Antibody (HPAB-0736-YJ-VHH) | ELISA | Camelid VHH |
| HPAB-0737-YJ-VHH | Camelid Anti-MUC1 Recombinant Single Domain Antibody (HPAB-0737-YJ-VHH) | ELISA | Camelid VHH |
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To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-439MZ, RRID: AB_2941838)
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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